Review of Apoquel Chewable Tablets for Dogs
In the world of veterinary medicine, a new solution has emerged to help alleviate the discomfort of dogs suffering from atopic dermatitis - Apoquel Chewable Tablets. This synthetic Janus Kinase (JAK) inhibitor has been making waves for its targeted approach to managing itching and inflammation associated with this condition.
Apoquel Chewable works by selectively inhibiting JAK enzymes, which are crucial in the signalling pathways of pro-inflammatory and pruritogenic cytokines. By blocking these enzymes, Apoquel disrupts the activity of cytokines such as interleukin-31 (IL-31), known to cause itch and inflammation. This targeted mechanism provides rapid and focused relief from allergic itching, without broadly suppressing the immune system.
The active ingredient in Apoquel, oclacitinib, specifically inhibits JAK1 and JAK3, which mediate the signalling of various cytokines involved in the itch and inflammatory response associated with allergic and atopic dermatitis in dogs. This targeted approach reduces itching typically within 4 hours and controls allergic skin inflammation effectively, setting Apoquel apart from steroids or cyclosporine by minimising overall immune suppression and side effects.
It's important to note that adverse reactions in dogs when using Apoquel are rare. However, potential side effects may include lethargy. Apoquel is only labeled for use in dogs and has not been cleared by the FDA for use in cats.
Apoquel Chewable is a prescription-only medication, not available over-the-counter. It's FDA-approved for dogs 12 months and older to control itching associated with allergic dermatitis and atopic dermatitis. The average shelf life for Apoquel chewable tablets is 24 months. Do not administer Apoquel chewable tablets past the expiration date listed on the packaging.
There are no known interactions between Apoquel and concurrent use of antihistamines, but it's always advisable to consult with your veterinarian before using Apoquel with any other medication.
In summary, Apoquel Chewable offers a promising solution for managing canine atopic dermatitis. By blocking JAK-dependent cytokine pathways that drive allergic itching and inflammation, Apoquel provides fast and focused symptom relief, differentiating it from traditional treatments. Always consult with your veterinarian before administering Apoquel to your pet.
Apoquel, initially developed for human health-and-wellness, has now been adapted for pets and specifically dogs, providing a novel solution in the realm of veterinary medicine, focusing on the management of atopic dermatitis. This lifestyle-altering treatment, when combined with proper fitness-and-exercise and diet for pets, could potentially contribute to their overall well-being and quality of life. It is essential to remember that while Apoquel may offer significant benefits, it should be used responsibly and under the guidance of a veterinary professional.
