Pain management solution offered by Promex and Realeve honored by MedTech Breakthrough Awards
In the ever-evolving world of medical technology, Realeve, a pioneering medical device company, is making significant strides in the treatment of central nervous system disorders. Dr. Peter Bonutti, the founder and CEO of Realeve, brings over 30 years of experience and more than 500 patents in the medtech field to this venture.
At the heart of Realeve's innovation is the Pulsante system. This groundbreaking technology is the first externally powered implantable neuromodulation device system designed to treat central nervous system disorders, including strokes and cluster headaches. The system is powered by the Pulsante RC-200 handheld device, which has the potential to treat a range of brain-related conditions.
The MedTech Breakthrough Awards program, conducted by MedTech Breakthrough, recognised the potential of Pulsante, awarding Realeve and Pulsante the 2025 Best New Pain Management Technology Solution. This accolade underscores the system's promise in improving healthcare delivery, offering patients greater independence, and improving their quality of life.
Pulsante provides relief for patients suffering from conditions such as chronic migraine and neuropathic pain. In studies of chronic cluster headaches, 75% of participants reported a significant reduction in headache frequency and intensity using the system over a four-week period. Moreover, Pulsante offers a drug-free, safe, and effective treatment option that can be used at home, reducing the need for clinic visits and side effects associated with pharmaceuticals.
The Pulsante system features a minimally invasive, battery-free, wireless compact SPG microstimulation implant. This design offers a more holistic treatment approach for chronic pain and neurological disorders. Furthermore, future iterations of Pulsante technology may incorporate AI-based pain tracking and predictive analytics, further enhancing its potential.
Neurostimulation has shown promise in treating conditions linked to nerve dysfunction, such as sleep disorders and anxiety. Dr. Bonutti, the visionary behind Pulsante, expects the technology to treat other conditions linked to nerve dysfunction in the future.
While Realeve is making headway in central nervous system disorder treatment, other companies are also pushing the boundaries of neurostimulation technology. For instance, Nalu Medical's Nalu Neurostimulation System features a battery-free, miniaturized implantable pulse generator that delivers precise electrical stimulation to targeted peripheral nerves. Similarly, Bioventus' TalisMann™ device combines patented electric field conduction technology with an integrated pulse generator designed to potentially target deeper and larger peripheral nerves.
In conclusion, Realeve's Pulsante system, with its innovative design and potential for treating a wide range of conditions, is revolutionizing the approach to chronic pain and neurological disorders. Meanwhile, companies like Nalu Medical and Bioventus are pushing the boundaries of peripheral nerve pain management through neurostimulation, marking a new era in the field of medical technology.
[1] Nalu Medical. (n.d.). Nalu Neurostimulation System. Retrieved from https://nalumedical.com/nalu-neurostimulation-system/ [2] Bioventus. (n.d.). TalisMann™. Retrieved from https://www.bioventus.com/products/talismann [3] FDA. (n.d.). Nalu Neurostimulation System. Retrieved from https://www.fda.gov/medical-devices/pre-market-approval-pma/nalu-neurostimulation-system-p190066 [4] FDA. (n.d.). TalisMann™. Retrieved from https://www.fda.gov/medical-devices/pre-market-approval-pma/talismann-p190047
Realeve's Pulsante system, a groundbreaking digital health technology, is leveraging the power of science to revolutionize the treatment of medical-conditions such as central nervous system disorders, chronic migraine, and neuropathic pain. This system, awarded as the 2025 Best New Pain Management Technology Solution by MedTech Breakthrough, offers a drug-free, safe, and effective treatment option that enhances health-and-wellness and improves patients' quality of life. Furthermore, advancements in neurostimulation, like Nalu Medical's Nalu Neurostimulation System and Bioventus' TalisMann™ device, are also pushing the boundaries of treatment for various health-related conditions, particularly neurological disorders and peripheral nerve pain management.
