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Neuroblastoma: Understanding the Cancer Affecting Infants

Discover the signs and stages of neuroblastoma. See how recent advancements in immunotherapy are improving outcomes for young patients.

This is a picture of a concert. In this image there is a stage. In the center of the image there is...
This is a picture of a concert. In this image there is a stage. In the center of the image there is a person standing in front of the microphone playing guitar. In the background there is a man seated playing drums. On the left there are speakers. In the background there are lights.

Neuroblastoma: Understanding the Cancer Affecting Infants

Neuroblastoma, a cancer that affects immature cells of the sympathetic nervous system, is most common among infants. Approximately 700 new cases are diagnosed annually in the United States. Symptoms include lumps, bulging eyes, abdominal swelling, bone pain, weakness, and skin changes. It develops as a solid tumor, often in the adrenal gland, pelvis, abdomen, neck, or chest. Most cases aren't inherited, but about 1-2% are. Treatment depends on the child's age and the cancer's stage, with significant progress made in immunotherapy for relapse patients.

Neuroblastoma is diagnosed through blood and urine tests, bone marrow biopsy, imaging scans, and other tests. It has four stages, with stage 4 being the most advanced and severe. Treatment options include surgery, chemotherapy, radiation therapy, and targeted immunotherapy. The outlook varies, with five-year survival rates ranging from about 40 to 95 percent. If it progresses, it can spread to bones, lymph nodes, and skin. Most cases aren't inherited, but about 1-2% are, following an autosomal dominant pattern.

Neuroblastoma is a serious condition that requires prompt medical attention. With proper treatment, many children can overcome this disease. Recent advancements in immunotherapy have significantly improved prognosis for relapse patients. As with any cancer, early detection and appropriate treatment are crucial for the best possible outcome.

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