Cost, effects, applications, dosages, and additional details about Voranigo: a medicinal substance.
Rewritten:
Voranigo is an oral medication used for certain types of brain tumors in adults and kids aged 12 and above. This medication contains the active ingredient vorasidenib and is classified as an isocitrate dehydrogenase-1 and isocitrate dehydrogenase-2 inhibitor, or a labeled type of targeted cancer therapy.
The Food and Drug Administration (FDA) approved Voranigo to treat low-grade grade 2 astrocytomas and oligodendrogliomas, a group of brain tumors that begin in distinct brain cells, in eligible patients. To learn more about the specific usage of Voranigo, check out the "Voranigo Uses" section.
Drug Details
Here's a rundown of key Voranigo information:
- Drug Class: Voranigo belongs to a targeted cancer therapy class, aiming to inhibit abnormal IDH1 and IDH2 enzymes in brain tumor cells.
- Generic Available?: No, Voranigo is currently only sold under the brand name.
- Prescription Required?: Yes, a prescription is necessary to get this medication.
- Controlled Substance?: No, Voranigo is not a controlled substance.
less than 40 kg (about 88 pounds [lb])
Generic Form
20 mg once per day
As of now, Voranigo is only available in brand-name form. A generic equivalent is unavailable.
Cost and Coupons
40 kg or more
You'll find that the cost of Voranigo varies, as it depends on factors like your insurance coverage, location, and the pharmacy you choose.
40 mg once per day
If finances are a concern or you need help understanding your prescription coverage, several options can assist you, such as the ServierONE program. You can learn more by calling 800-813-5905 or visiting their website.
Side Effects
Mild to severe side effects can occur while taking Voranigo. Here are a few to keep in mind:
- Mild Side Effects: Fatigue, headache, nausea, diarrhea, constipation, decreased appetite, muscle or joint pain, COVID-19, and reduced white blood cell count or increased liver enzymes.
- Serious Side Effects: Seizures, liver problems, and allergic reactions.
• ciprofloxacin (Cipro)• cyclosporine (Neoral, others)• fluvoxamine (Luvox)• phenytoin (Dilantin, Phenytek)• rifampin (Rifadin, Rimatane)• hormonal forms of birth control, such as the combined pill, minipill, or patch
In case of severe side effects, contact your doctor immediately or call 911 if symptoms seem life-threatening.
Comparable Medications
Alternatives to Voranigo for brain tumor treatment depend on tumor type, primarily focused on IDH mutations. Potential options may include:
- Other IDH Inhibitors, such as ivosidenib (Tibsovo) and enasidenib (Idhifa)
- Standard treatments like surgery, radiation therapy, and chemotherapy (ex. temozolomide)
- Clinical trials exploring novel targeted agents, immunotherapies, or combination therapies for non-IDH-mutant or resistant tumors
- Symptom-management treatments to control seizures, headaches, or neurological deficits
Choosing among these alternatives depends on molecular tumor testing, clinical evaluation, and expert consultation to tailor therapy effectively.
- Voranigo, a medication for certain brain tumors, is a targeted cancer therapy that inhibits abnormal IDH1 and IDH2 enzymes in brain tumor cells, classifying it as a type of targeted cancer drug.
- While participating in medical-conditions management such as cancer treatment, it is crucial to be aware of other neurological disorders, which might necessitate the use of drugs like ciprofloxacin, cyclosporine, fluvoxamine, phenytoin, or hormonal forms of birth control.
- If you are interested in learning about the pharmaceutical aspect of cancer care, check out the oncology department at your local hospital or research recent studies in the field of science related to health-and-wellness and neurological-disorders.
- Aside from Voranigo, other brain tumor treatment options might include other IDH inhibitors like ivosidenib and enasidenib, standard treatments like surgery, radiation therapy, and chemotherapy, clinical trials, or symptom-management treatments.
- Before starting any new medication, be sure to consult your medical professional and discuss potential side effects, such as mild side effects like fatigue, headache, nausea, and reduced white blood cell count, or serious side effects like seizures and liver problems.
