Autoimmune Atrophic Gastritis: A Serious Condition on the Rise
Autoimmune Atrophic Gastritis (AG), a condition where the immune system attacks the stomach lining, poses significant health risks. It's more prevalent among Hispanics and Asians, and increases stomach cancer risk. Symptoms can include stomach pain, weight loss, and vitamin B12 deficiency, leading to anemia and neurological issues.
AG often stems from an H. pylori bacterial infection, which disrupts the stomach's protective mucus barrier. Over time, this can lead to chronic inflammation and cell destruction. The condition can also be autoimmune, triggered when the immune system mistakenly targets healthy stomach cells. Regardless of cause, AG requires lifelong vitamin B12 substitution and regular gastroscopic monitoring to prevent complications like pernicious anemia and gastric carcinoma.
Diagnosis involves blood tests for pepsinogen, gastrin, B12 levels, and antibodies, as well as a stomach biopsy. Symptoms may include stomach pain, nausea, vomiting, loss of appetite, unexpected weight loss, stomach ulcers, and iron deficiency anemia. Autoimmune AG can cause B12 deficiency, leading to weakness, lightheadedness, dizziness, chest pain, heart palpitations, and neurological issues.
AG is a serious condition that requires careful management. Early diagnosis and treatment can help prevent severe complications. If you experience symptoms, it's crucial to consult a healthcare provider for proper evaluation and treatment.
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